Hadassah

BioLineRx to Commence Phase 1 Stem Cell Trial at Hadassah Medical Organization

Thursday, Jun 19 2014

BioLineRx Ltd. has received approval from the Israeli Ministry of Health to commence a Phase 1 trial for BL-8040, a novel treatment for mobilizing stem cells from the bone marrow for treating acute myeloid leukemia, as well as other hematological malignancies. The study is expected to begin during the third quarter of 2014 at the Hadassah Medical Organization.

Dr. Kinneret Savitsky, Chief Executive Officer of BioLineRx, explains that stem cell mobilization is being used more and more as a method of collecting stem cells, instead of the traditional surgical procedure of bone marrow harvesting. Current treatment regimens, she notes, involve daily injections of G-CSF, a growth factor that stimulates the bone marrow to make white blood cells.

These injections are given for 4-6 days with or without the addition of a mobilizing agent such as Plerixafor (Mozobil). A previous Phase 1/2 study in multiple myeloma patients revealed that BL-8040 given as a single injection in combination with G-CSF injections was highly effective in mobilizing stem cells. The current trial aims to evaluate the mobilization capacity of one or two injections of BL-8040 as a stand-alone therapy, which could significantly shorten treatment and reduce costs.

Comments

No comments yet.
First Name
Email
Comment
Enter this word:

Related Stories

alt_text

Wednesday, Nov 14 2018

A Hassidic Mother’s Promise to Donate a Kidney: Mission Accomplished

A young girl named Esti had a best friend named Tali whose father had kidney disease. He passed away before a kidney transplant could save his life.

READ MORE ›
alt_text

Friday, Nov 9 2018

Children with Low Vision Receive Unique Care at Hadassah

“The vision of world-renowned Prof. Isaac Caesar Michaelson, former Director of the Hadassah Medical Organization’s Department of Ophthalmology, of creating in 1973 The Jerusalem Institute for the Prevention of Blindness still amazes me,” says Dr. Claudia Yahalom, current head of the renamed Michaelson Institute for Rehabilitation of Vision at Hadassah Hospital Ein Kerem.

READ MORE ›
alt_text

Tuesday, Nov 6 2018

Hadassah Staff Saves Seven-Year-Old From Deadly Scorpion Bite

The intensity of his cry alerted Elisha Alush’s parents that something serious had happened to their seven-year-old. He ran in from the backyard of their home near Jericho, north of Jerusalem, screaming, “My foot, my foot.” And then he lost consciousness.

READ MORE ›
alt_text

Thursday, Nov 1 2018

Hadassah Saves Soccer Fan’s Life in Newly Inaugurated Heart Center

Mickey Peretz, age 36, began his evening at a Beitar Jerusalem soccer game. Little did he know that he would end the evening being the first patient to receive a life-saving heart catheterization in Hadassah Hospital Ein Kerem’s brand new Irma and Paul Milstein Heart Center.

READ MORE ›

Donation Questions

donorservices@hadassah.org

(800) 928-0685

Membership Questions

membership@hadassah.org

(800) 664-5646

Missions Department

missions@hadassah.org

(800) 237-1517

Contact Us

40 Wall Street

New York, NY 10005

support@hadassah.org

More ›

Show More