Hadassah

Hadassah Cardiologist is Key Researcher in Identifying Genetic Heart Mutation

Tuesday, Sep 1 2015

"Some 2.4 percent of the population suffers from mitral valve prolapse, where one of the valves that controls blood flow through the heart doesn't close properly,” reports Dr. Durst.

Dr. Ronen Durst, a senior cardiologist at the Hadassah Medical Organization and a Hebrew University researcher, is a key member of the international team that has identified a genetic mutation linked to mitral valve prolapse.

Dr. Durst is the first author of the article about this genetic mutation published in the prestigious British science journal, Nature.

The international collaborative research team, led by Massachusetts General Hospital (MGH), where Durst was working in the Center for Human Genetic Research and the Division of Cardiology, had been seeking a genetic connection to this common cardiac problem, which often runs in families. The research led to the discovery of the mutation in the DCHS1 gene in affected members of three families.

"Some 2.4 percent of the population suffers from mitral valve prolapse, where one of the valves that controls blood flow through the heart doesn't close properly,” reports Dr. Durst. “This abnormality,” he brings out, “often causes serious problems in heart rhythm, infections, and even sudden death.”

Dr. Robert Levine of MGH’s Corrigan Minehan Heart Center, co-senior author of the Nature paper, notes: “This finding can teach us how to prevent this inborn disease from manifesting as an illness in people who inherit mutated forms of the gene. Understanding how defects in this gene cause errors in early valve formation can point to ways we can prevent the progression of this condition to keep the valve and the heart healthy and help the patient avoid complications.”

Nature's acceptance of this study, Dr. Durst says, “underlines its international importance and strengthens the link between researchers at Hadassah Hospital and the Hebrew University of Jerusalem with colleagues in prestigious laboratories abroad, such as Harvard and the hospitals with which it is affiliated.”

Comments

From: dvasha on September 10, 2015
pls email this article to me and how I can stay aware of significant developments. Tx.
First Name
Email
Comment
Enter this word:

Related Stories

alt_text

Tuesday, Jun 20 2017

Send in the Clowns: A Hadassah UK Dispatch

This week Hadassah UK (HUK) brought in one of the Hadassah Medical Organization's best and more unusual, head medical clown David Barashi (DuSH).

READ MORE ›
alt_text

Friday, Jun 16 2017

Hadassah’s Director General Receives Honorary PhD from Cyprus Medical School

For sharing his knowledge and experience with senior officials in the Cyprus medical system, Prof. Zeev Rotstein, Director General of the Hadassah Medical Organization, was awarded an honorary PhD from the St. George University of London’s Medical Program at the University of Nicosia Medical School in Cyprus.

READ MORE ›
alt_text

Thursday, Jun 8 2017

Hadassah Doctors Discover Bullet
in 12-Year-Old’s Arm

Muhammad Baduan, age 12, had been experiencing pain in his arm on and off for months. Hadassah Hospital Ein Kerem Emergency Room physicians put an end to the boy’s pain when they solved the mystery: Muhammad had a 22-millimeter bullet hidden in that arm--a bullet that had been shot into the air as part of a post-wedding ceremony celebration.

READ MORE ›
alt_text

Monday, Jun 5 2017

Hadassah Cutting-Edge Neuropsychiatrist Keynotes Alzheimer’s Conference

“The key is to give medicines much earlier--before the brain material has been destroyed by Alzheimer’s disease,” Dr. Shahar Arzy, head of the Hadassah Medical Organization’s Computational Neuropsychiatry Laboratory, told his audience at the Alzheimer’s Foundation of America (AFA)’s New York Educational Conference on May 5, 2017.

READ MORE ›

Donation Questions

donorservices@hadassah.org

(800) 928-0685

Membership Questions

membership@hadassah.org

(800) 664-5646

Missions Department

missions@hadassah.org

(800) 237-1517

Contact Us

40 Wall Street

New York, NY 10005

support@hadassah.org

More ›

Show More