Hadassah

Hadassah Ophthalmology Department Research Highlighted by JAMA

Tuesday, Jun 12 2018

Thanking the Hadassah Medical Organization’s researchers for their ”excellent submission” to JAMA Ophthalmology regardinga multi-center international study of the variable effectiveness of treatment for neovascular age-related macular degeneration (nAMD),the editors explained that their article was one of just a few from 12 JAMA on-line journals to be highlighted in The JAMA Network Reader this weekend.

The Reader is available free to everyone around the world at http://app.jamanetwork.com.

Prof. Itay Chowers, head of Hadassah’s Department of Ophthalmology, and Michelle Grunin, a PhD student of his at the time, conducted this study in collaboration with colleagues in Australia, Canada, Germany, the Netherlands, Northern Ireland, Norway, Switzerland, United Kingdom, and the United States. Together, they identified genetic factors that are associated with variability in response to a particular type of therapy for patients with nAMD, where abnormally high levels of vascular endothelial growth factor (VEGF) are secreted in the eyes, promoting the growth of new abnormal blood vessels. Anti-VEGF injection therapy blocks this growth.

The authors’ findings led them to propose that “there is a limited contribution of common genetic variants to variability in nAMD treatment response. Our results suggest that rare protein-altering variants in the C10orf88 and UNC93B1 genes are associated with a worse response to anti-VEGF therapy in patients with nAMD, but these results require further validation in other cohorts.”

Read the full article in JAMA Ophthalmology.

Comments

No comments yet.
First Name
Email
Comment
Enter this word:

Related Stories

alt_text

Monday, Jun 11 2018

Ruth Radiano: Passionate New Director of Nursing at Hadassah Hospital Mount Scopus

Translating her passion and professionalism into action, Ruth Radiano, the new Director of Nursing at Hadassah Hospital Mount Scopus, brings a background of 26 years of nursing at Hadassah.

READ MORE ›
alt_text

Thursday, Jun 7 2018

Former NYC Mayor Giuliani Calls Hadassah Hospital a Blessing

Former New York City Mayor Rudy Giuliani and his partner Dr. Maria Ryan, CEO of Cottage Hospital in Woodsville, New Hampshire visited Hadassah Medical Organization in Jerusalem today to get an update on Hadassah’s management of terror events.

READ MORE ›
alt_text

Thursday, Jun 7 2018

Hadassah Researchers Develop Definitive Biomarker for Cardiac Muscle Death and Link it to Death from Sepsis

Hadassah Medical Organization researchers, in collaboration with colleagues at the Hadassah-Hebrew University School of Medicine, have developed a blood test which definitively detects death of cardiac muscle cells following an acute heart attack and in the case of sepsis.

READ MORE ›
alt_text

Thursday, May 31 2018

Julie Benbenishty: Bridging the Geographical Divide in Nursing Care

Julie Benbenishty, Nurse Coordinator of the Hadassah Medical Organization’s Trauma Unit, was concerned about continuity of care when her patients from the West Bank and Gaza left Hadassah. “The minute they returned home,” she relates, “I had no one to be in touch with about follow-up care.”

READ MORE ›

Donation Questions

donorservices@hadassah.org

(800) 928-0685

Membership Questions

membership@hadassah.org

(800) 664-5646

Missions Department

missions@hadassah.org

(800) 237-1517

Contact Us

40 Wall Street

New York, NY 10005

support@hadassah.org

More ›

Show More