Hadassah

Hadassah Research Leads to Patent for Diabetes-Related Oral Delivery Technology

Thursday, Jan 22 2015

Oramed Pharmaceuticals Inc., focused on the development of oral drug delivery systems including an oral insulin pill based on Hadassah Medical Organization research, has received a patent from the Israel Patent Office for its invention, “Methods and Compositions for Oral Administrations of Exenatide.”

Eexenatide, a glucagon-like peptide-1 (GLP-1) analog, is a hormone which induces insulin release at increased glucose levels and causes a feeling of satiety, resulting in reduced food intake and weight loss. Currently, it is only marketed in injectable form. Oramed’s oral GLP-1 capsule, according to Oramed, could significantly increase compliance and become a valuable tool in the treatment of diabetes.

Oramed was founded in 2006 by Dr. Miriam Kidron, a senior researcher in the Diabetes Unit at Hadassah, who continues to serve as the company’s chief scientist. A pharmacologist and biochemist, Dr. Kidron earned her PhD in biochemistry from the Hadassah-Hebrew University and earned the Bern Schlanger Award for her work in diabetes research. Formerly a visiting professor at the Medical School at the University of Toronto, she is a member of the American, European, and Israeli diabetes associations.

Oramed's Protein Oral Delivery (PODTM) technology is based on over 30 years of research by top scientists at Hadassah. Oramed is seeking to revolutionize the treatment of diabetes through its proprietary flagship product, an orally ingestible insulin capsule (ORMD-0801). Having completed separate Phase IIa clinical trials, the company anticipates the initiation of separate Phase IIb clinical trials, in patients with both type 1 and type 2 diabetes, under an Investigational New Drug application with the United States Food and Drug Administration.

Read more

Comments

No comments yet.
First Name
Email
Comment
Enter this word:

Related Stories

alt_text

Thursday, Jul 19 2018

Hadassah Doctors in Forefront of Diabetes Prevention and Treatment

“Diabetes is on track to become the largest epidemic in human history.” So says Dr. Gil Leibowitz, incoming head of the Hadasah Diabetes Center at Hadassah Hospital Ein Kerem, and himself a diabetic since the age of seven.

READ MORE ›
alt_text

Wednesday, Jul 11 2018

Improving Kidney Health of Premature Babies

Is the TV hit show Grey's Anatomy taking its inspiration from Hadassah Hospital? After all, cast members did visit Hadassah Ein Kerem in 2011. Dr. Oded Volovelsky, Head of Hadassah's new Pediatric Nephrology Unit says, only half-jokingly, that TV doc Meredith Grey might have read his research.

READ MORE ›
alt_text

Wednesday, Jul 11 2018

Hadassah Cancer Specialists Explore Link Between Colorectal Cancer and BRCA Mutations

Looking further into the link between colorectal cancer and BRCA 1 and 2 genetic mutations, researchers from the Hadassah Medical Center’s Sharett Institute of Oncology, together with colleagues from Chaim Sheba Medical Center, analyzed data from 32 patients with lower gastrointestinal cancers.

READ MORE ›
alt_text

Monday, Jul 9 2018

World Hepatitis Day: Hadassah’s Contribution to the Global Battle Against this Disease

“Hadassah Medical Organization's (HMO) greatest contribution to the global battle against Hepatitis are the vaccines that have been developed here,” said Prof. Daniel Shouval, as we mark World Hepatitis Day on July 28.

READ MORE ›

Donation Questions

donorservices@hadassah.org

(800) 928-0685

Membership Questions

membership@hadassah.org

(800) 664-5646

Missions Department

missions@hadassah.org

(800) 237-1517

Contact Us

40 Wall Street

New York, NY 10005

support@hadassah.org

More ›

Show More