Hadassah

“Stunning Results” Continue with Hadassah’s Stem Cell Treatment to Reverse MS

Thursday, Sep 15 2016

Prof. Dimitrios Karussis.

The Hadassah Medical Center is continuing to receive positive findings with its Phase II clinical trial using its unique stem cell approach to stop the progression and reversing the disabilities of multiple sclerosis.

The Hadassah-developed treatment involves intrathecal injection--injection of the patient’s own bone marrow-derived stem cells directly into the spinal fluid--so that the cells circulate all the way around the brain and the spinal cord, where they are needed.

Hadassah began its clinical trials with ALS and MS patients in 2007, marking “the first time this approach had been applied in neurological diseases,” explains Principal Investigator Prof. Dimitrios Karussis, head of Hadassah’s Multiple Sclerosis Center. “The safety data were excellent,” he relates. “There was absolutely no serious adverse event, and we saw that, as a secondary observation-- because there was no placebo with which to compare it --patients with ALS stopped progressing for at least six months, the length of the study.”  In addition, he says, “patients with multiple sclerosis sometimes had a significant improvement in their disability.”

Fast forward to 2016 and Prof. Karussis is now optimistic about his Phase II study which began in January 2015. To date, about 2/3 out of the 48 patients to be enrolled have been recruited and treated. “This trial,” explains Prof. Karussis, “is a large, randomized double-blind, placebo-controlled study. While the patients in the control group will not know if they are initially getting the actual treatment or a placebo, the trial contains a crossover design so that eventually everyone will get the stem cell treatment, although some patients will receive the actual treatment six months later.”

Where will these clinical trials lead if they continue to yield positive findings? Prof. Karussis replies:  “We can say that if things continue to go like this and continue in the same direction, this will definitely change the face of neurology and the management of these diseases, which have been very impotent, you could say, all these years.”  Read the full article in The Jerusalem Post

Comments

From: Olayemi Ajala on November 26, 2017
My mum has MS I’m from london she can’t walk or move her legs but can move her arms can I plan to see you I want my Mum to walk again
From: Laura on November 22, 2017
Hello ! can you tell me how you can get on the trial in Israel..its for my lovely husband !! thank you laura
From: Helen on November 5, 2016
I have Lupus and am interested to learn what new Research you might have ready to bring to the market.
From: Grecia on October 21, 2016
What amazing results! Where can I find info about doctor Karussis lecture plans for this year? Thank you!
First Name
Email
Comment
Enter this word:

Related Stories

alt_text

Friday, Jun 22 2018

To Save Their Children - The Mothers Came Secretly From Syria to Hadassah

Repairing the Hearts of Syrian Children at Hadassah Hospital in Jerusalem.

READ MORE ›
alt_text

Thursday, Jun 21 2018

Traveling with Ruth

Ruth Radiano, Head Nurse at Hadassah Hospital Mount Scopus, is an extraordinary woman, whose resume reads like a novel. I recently had the distinct pleasure of meeting her and hearing her speak, and in just five minutes with her, I felt as though I was with a Hadassah sister.

READ MORE ›
alt_text

Wednesday, Jun 20 2018

First in Israel: Hadassah Uses Innovative Technology to Treat Cancer in Spine

A multidisciplinary team at Hadassah Hospital Ein Kerem recently employed an innovative technology to treat cancer metastases near the spinal cord--a first for Israel.

READ MORE ›
alt_text

Tuesday, Jun 19 2018

American Journal of Ophthalmology Article Celebrates the Centennial of Hadassah Ophthalmology

The centennial anniversary of the Hadassah Medical Organization's Department of Ophthalmology is celebrated in the May issue of the American Journal of Ophthalmology, with an article by the immediate past director, Prof. Jacob Pe'er, and the current director, Prof. Itay Chowers.

READ MORE ›

Donation Questions

donorservices@hadassah.org

(800) 928-0685

Membership Questions

membership@hadassah.org

(800) 664-5646

Missions Department

missions@hadassah.org

(800) 237-1517

Contact Us

40 Wall Street

New York, NY 10005

support@hadassah.org

More ›

Show More