Hadassah

Hyperpolarizing Phosphates to Diagnose Disease: a Hadassah World First

Wednesday, Aug 30 2017

What can the phosphorus in your blood tell you about your health?

Researchers in the Hadassah Medical Organization’s imaging department have developed a world-first noninvasive diagnostic method to measure phosphate levels in the body’s tissues that can alert them to the presence of diseases such as cancer.

Their discovery appears in the August 24, 2017 online issue of Nature Communications.

The novel procedure is being hailed as a breakthrough because it is currently impossible to test the acidity level in the tissues of the human body without performing an invasive procedure. In addition, examining a tissue sample for this purpose is not a diagnostic option because body tissue changes within seconds. With this new diagnostic tool, however, researchers can determine the level of acidity which can vary, for example, when there is a cancerous tumor present.

Dr. Rachel Katz-Brull, who heads Hadassah’s research team, explains: “This is a diagnostic tool related to the metabolic function of the cells in a tumor or other suspicious tissue. Such a measure could allow, for example, a more precise identification of a tumor as malignant or benign and help test the efficacy of treatment.”

With this new technology, a patient could be saved from invasive procedures such as a biopsy to determine whether a tumor is cancerous. Instead, via this high-tech MRI imaging, the phosphate is caused to “shine” more than 10,000 times brighter, enabling the researchers to see the nucleus of the phosphorous-containing cell. And this clarity is achieved without injecting radioactive materials into the patient. Hadassah is one of the few medical centers in the world that is equipped with this technology.

Dr. Katz-Brull completed postdoctoral research at Harvard University and Beth Israel-Deaconess Hospital in Massachusetts. When she returned to Israel, she established the Center for Hyperpolarized MRI Molecular Imaging in Hadassah’s radiology department.

Read more in the Jerusalem Post.

Comments

No comments yet.
First Name
Email
Comment
Enter this word:

Related Stories

alt_text

Wednesday, Feb 20 2019

Jerusalem Basketball Star Undergoes Knee Surgery at Hadassah

Chris Johnson, a star basketball player with Hapoel Bank Yahav Jerusalem, underwent successful knee surgery at Hadassah Hospital Mount Scopus.

READ MORE ›
alt_text

Wednesday, Feb 20 2019

Hyper-Diamonds and More ”Enlightening” MRIs

The Hadassah Medical Organization recently hosted a meeting of scientists from around the world, who are working together on a special research project called HyperDiamond.

READ MORE ›
alt_text

Tuesday, Feb 19 2019

Marathoner Is Helicoptered to Hadassah After Collapsing During Race

Shahar David, age 46, had planned to run 10 kilometers in the Dead Sea Marathon, but he collapsed after kilometer 6. A helicopter transported him to Hadassah Hospital Ein Kerem, where he underwent an emergency cardiac catheterization that saved his life.

READ MORE ›
alt_text

Thursday, Feb 7 2019

Six Miscarriages, a Severe Liver Disease, and a Dream

Oshrat Ohana Nagar was a busy newspaper journalist, a self-proclaimed workaholic, and a mother of two children. Shortly after the birth of her second child, however, she began to experience pain throughout her body.

READ MORE ›

Donation Questions

donorservices@hadassah.org

(800) 928-0685

Membership Questions

membership@hadassah.org

(800) 664-5646

Missions Department

missions@hadassah.org

(800) 237-1517

Contact Us

40 Wall Street

New York, NY 10005

support@hadassah.org

More ›

Show More