Hadassah

Placental Stem Cells Prove Successful in Bringing Little Girl to Recovery at Hadassah

Tuesday, May 15 2012

Using placental mesenchymal stem cells--which proved effective in pre-clinical trials--physicians at the Hadassah University Medical Center rescued the life of a seven-year-old Romanian girl whose two bone marrow transplants were not triggering the repair needed to save her life.

“B” was suffering from severe aplastic anemia, a disorder where the bone marrow does not produce sufficient new cells to replenish the blood. For the last 10 months, she had been hospitalized at Hadassah in critical condition. While her body accepted the two transplants from two different donors, the donated bone marrow was unsuccessful in getting her body to take over the replenishment process and produce new red blood cells. Prof. Reuven Or, head of the Sidney Weisner Department of Bone Marrow Transplantation and Cancer Immunology, decided to speak with Prof. Rafi Gorodetsky, Director of Hadassah’s Biotechnology and Radiobiology Laboratory in the Sharrett Institute of Oncology, who was conducting stem cell research sponsored by Pluristem Therapeutics, an Israeli bio-tech company which develops placental mesenchymal cells.  Prof. Gorodetsky's pre-clinical trial showed success in treating radiated mice with the Pluristem cells. (See ”Placental Cells Found to Have Potential to Mitigate Acute Radiation Syndrome,” in .)

After receiving the approvals of Hadassah's Helsinki Committee and Israel’s Ministry of Health, Hadassah’s physicians gave “B” two shots of the Pluristem cells, injecting them into her thigh muscle. The recovery was so significant that “B” was able to leave the hospital.

"This is a moment every physician and researcher waits for," says Prof. Or. "We now have a new tool and I always prefer to use biological substance over chemical components." Prof. Or cautions, however, that this is only one single case and 
the treatment still requires full scientific exploration and validation. Scientists at Pluristem and Prof. Or will now discuss “next steps” and how to widen the scope of their studies.

“Whatever happens next,” comments Ron Krumer, Director of Hadassah’s External Relations Department, “we can enjoy another story of life saving at Hadassah--a combination of the ingenuity of an Israeli biotech firm, Hadassah research, and Hadassah clinical excellence.”

Comments

No comments yet.
First Name
Email
Comment
Enter this word:

Related Stories

alt_text

Thursday, Feb 7 2019

Six Miscarriages, a Severe Liver Disease, and a Dream

Oshrat Ohana Nagar was a busy newspaper journalist, a self-proclaimed workaholic, and a mother of two children. Shortly after the birth of her second child, however, she began to experience pain throughout her body.

READ MORE ›
alt_text

Wednesday, Feb 6 2019

Hadassah Hematologist Dina Ben-Yehuda: Healer, Researcher, Mentor, and Dean

During this age of big data and artificial intelligence, Prof. Dina Ben-Yehuda, head of the Hadassah Medical Organization’s Department of Hematology and now also the first female dean of the Hadassah-Hebrew University School of Medicine, believes that the “role of physician as healer is more necessary for patients than ever.”

READ MORE ›
alt_text

Wednesday, Feb 6 2019

Hadassah Eye Specialists Take Their Expertise to Nursing Homes

Saving nursing home residents from the burden of commuting to the hospital for eye examinations, Hadassah Medical Organization ophthalmologists and optometrists have begun bringing their expertise to the seniors’ home setting.

READ MORE ›
alt_text

Monday, Feb 4 2019

Hadassah Breast Imaging Specialist Offers Perspective on Preventive Care

The most important adversary to breast cancer screening is fear, says Dr. Tamar Sella, head of the Marlene Greenebaum Multidisciplinary Diagnostic Breast Center at the Hadassah Medical Organization.

READ MORE ›

Donation Questions

donorservices@hadassah.org

(800) 928-0685

Membership Questions

membership@hadassah.org

(800) 664-5646

Missions Department

missions@hadassah.org

(800) 237-1517

Contact Us

40 Wall Street

New York, NY 10005

support@hadassah.org

More ›

Show More